Behavioural Metabolution

Egbert, M. D., Barandiaran, X. E., & Di Paolo, E. A. (2012). Behavioral Metabolution: The Adaptive and Evolutionary Potential of Metabolism-Based Chemotaxis. Artificial Life, 18(1), 1–25. doi:10.1162/artl_a_00047

Again, the result of another fascinating collaboration with Matthew Egbert and Ezequiel Di Paolo: what would happen if early protocells had some capacity to move? We hypothesize that early metabolic evolution might have been bootstrapped throw behaviour generating a phenomenon we have called behavioural metabolution: the push-me pull-you positive feedback effect between behavioural selection of chemical environments and the evolution of metabolic networks that in turn influence behaviour that in turn selects chemical environments. Much more on the paper, download and read it!

A minimal model of metabolism-based chemotaxis

Egbert, M. D., Barandiaran, X. E., & Di Paolo, E. A. (2010). A Minimal Model of Metabolism-Based Chemotaxis. PLoS Comput Biol, 6(12), e1001004.

We present the first model of metabolism-based chemotaxis that accomplishes chemotaxis without transmembrane receptors or signal transduction proteins, through the direct modulation of flagellar rotation by metabolite concentrations. The minimal model recreates chemotactic patterns found in real bacteria, illuminating some previous work metabolism-dependent chemotaxis. A nice example of the inpiration taken from an autonomous perspective on agency, linking metabolism and behaviour.

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